Diagnostic Implications of Enhanced CD34 Expression in Hepatocellular Carcinoma: A Cross-Sectional Study

Background: Hepatocellular carcinoma is the most prevalent primary cancer of liver globally and responsible for majority cancer-related fatalities. The purpose research was to establish frequency enhanced cd34 expression in sinusoid-like vascular endothelial cells carcinoma. Methods: CMH Multan's Department Histopathology carried out a cross-sectional study. Histochemical staining performed. Before beginning technique, sections were washed phosphate buffer saline 5 minutes. usual immunohistochemistry method - Avidin Biotin Complex Method employed following hospital protocols. Results: 85 (67.5%) male 41 (32.5%) female patients among 126 studied cases. 54 (42.9%) from rural areas, while 72 (57.1%) urban areas. Diabetes 43 (34.1%), smoking found 10 (7.9%). Obesity 18 (14.3%), hypertension identified 74 (58.7%). Only (4.0%) our research's cases had family history HCC. Enhanced noted 106 (84.1%). Conclusion: There very high presentation can aid early recognition HCC proper care these improve their quality life. Keywords: Expression, carcinoma, cd34, Risk factors.